USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: IF5A1_HUMAN USC-OGP 2-DE database:  IF5A1_HUMAN IF5A1_HUMAN General information about the entry View entry in simple text format Entry name IF5A1_HUMAN Primary accession number P10159 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Eukaryotic translation initiation factor 5A-1; Short=eIF-5A-1; Short=eIF-5A1; AltName: Full=Eukaryotic initiation factor 5A isoform 1; Short=eIF-5A; AltName: Full=Rev-binding factor; AltName: Full=eIF-4D;. Gene name Name=EIF5A Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-5 {PLATELET 4-5} Homo sapiens (Human)   map experimental info   PLATELET_4-5 MAP LOCATIONS: SPOT OGP-0228: pI=5.04; Mw=19707 PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0586: pI=5.07; Mw=16680 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0846: pI=5.08; Mw=16811 UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1326: pI=5.17; Mw=17950 SPOT OGP-1327: pI=6.59; Mw=17706 SPOT OGP-1329: pI=4.39; Mw=16914 Cross-references UniProtKB/Swiss-Prot P63241; IF5A1_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name IF5A1_HUMAN Primary accession number P63241 Secondary accession number(s) A8K9A0 D3DTP2 P10159 Q16182 Q7L7L3 Q7Z4L1 Q9D0G2 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 138) Name and origin of the protein Description RecName: Full=Eukaryotic translation initiation factor 5A-1; Short=eIF-5A-1; Short=eIF-5A1; AltName: Full=Eukaryotic initiation factor 5A isoform 1; Short=eIF-5A; AltName: Full=Rev-binding factor; AltName: Full=eIF-4D; Gene name Name=EIF5A Encoded on Name=EIF5A Keywords 3D-structure; Acetylation; Alternative splicing; Complete proteome; Cytoplasm; Direct protein sequencing; Elongation factor; Endoplasmic reticulum; Hypusine; Membrane; mRNA transport; Nuclear pore complex; Nucleus; Protein biosynthesis; Protein transport; Reference proteome; RNA-binding; Translocation; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M23419; AAA58453.1; -; mRNA EMBL S72024; AAD14095.1; -; Genomic_DNA EMBL U17969; AAA86989.1; -; Genomic_DNA EMBL AY129319; AAN17514.1; -; mRNA EMBL AY129320; AAN17515.1; -; mRNA EMBL AY129321; AAN17516.1; -; mRNA EMBL AY129322; AAN17518.1; -; mRNA EMBL AK292615; BAF85304.1; -; mRNA EMBL CH471108; EAW90219.1; -; Genomic_DNA EMBL CH471108; EAW90220.1; -; Genomic_DNA EMBL CH471108; EAW90221.1; -; Genomic_DNA EMBL CH471108; EAW90222.1; -; Genomic_DNA EMBL BC000751; AAH00751.1; -; mRNA EMBL BC001832; AAH01832.1; -; mRNA EMBL BC030160; AAH30160.1; -; mRNA EMBL BC080196; AAH80196.1; -; mRNA EMBL BC085015; AAH85015.1; -; mRNA EMBL BC107779; AAI07780.1; -; mRNA CCDS CCDS11099.1; -. [P63241-1]; . CCDS CCDS45601.1; -. [P63241-2]; . PIR B31486; FIHUA; . RefSeq NP_001137232.1; NM_001143760.1. [P63241-2]; . RefSeq NP_001137233.1; NM_001143761.1. [P63241-1]; . RefSeq NP_001137234.1; NM_001143762.1. [P63241-1]; . RefSeq NP_001961.1; NM_001970.4. [P63241-1]; . RefSeq XP_005256566.1; XM_005256509.2. [P63241-1]; . UniGene Hs.104825; -; . UniGene Hs.534314; -; . PDB 1FH4; Model; -; A=1-154 PDB 3CPF; X-ray; 2.50 A; A/B=15-151 PDB 5DLQ; X-ray; 3.20 A; E/F=15-154 PDBsum 1FH4; -; . PDBsum 3CPF; -; . PDBsum 5DLQ; -; . ProteinModelPortal P63241; -; . SMR P63241; -; . BioGrid 108299; 48; . IntAct P63241; 27; . MINT MINT-1829069; -; . STRING 9606.ENSP00000336702; -; . TCDB 1.I.1.1.3; the nuclear pore complex (npc) family; . iPTMnet P63241; -; . PhosphoSitePlus P63241; -; . SwissPalm P63241; -; . BioMuta EIF5A; -; . DMDM 54037409; -; . DOSAC-COBS-2DPAGE P63241; -; . OGP P63241; -; . EPD P63241; -; . MaxQB P63241; -; . PaxDb P63241; -; . PeptideAtlas P63241; -; . PRIDE P63241; -; . TopDownProteomics P63241-1; -. [P63241-1]; . TopDownProteomics P63241-2; -. [P63241-2]; . DNASU 1984; -; . Ensembl ENST00000336452; ENSP00000336702; ENSG00000132507. [P63241-2]; . Ensembl ENST00000336458; ENSP00000336776; ENSG00000132507. [P63241-1]; . Ensembl ENST00000416016; ENSP00000396073; ENSG00000132507. [P63241-1]; . Ensembl ENST00000419711; ENSP00000390677; ENSG00000132507. [P63241-1]; . Ensembl ENST00000571955; ENSP00000458269; ENSG00000132507. [P63241-1]; . Ensembl ENST00000573542; ENSP00000459611; ENSG00000132507. [P63241-1]; . Ensembl ENST00000576930; ENSP00000459196; ENSG00000132507. [P63241-1]; . GeneID 1984; -; . KEGG hsa:1984; -; . UCSC uc002gfr.3; human. [P63241-1]; . CTD 1984; -; . DisGeNET 1984; -; . GeneCards EIF5A; -; . HGNC HGNC:3300; EIF5A; . HPA CAB005042; -; . HPA HPA061298; -; . MIM 600187; gene; . neXtProt NX_P63241; -; . OpenTargets ENSG00000132507; -; . PharmGKB PA27726; -; . eggNOG KOG3271; Eukaryota; . eggNOG COG0231; LUCA; . GeneTree ENSGT00390000003738; -; . HOVERGEN HBG001104; -; . InParanoid P63241; -; . KO K03263; -; . OMA IVEISTT; -; . PhylomeDB P63241; -; . TreeFam TF101534; -; . Reactome R-HSA-204626; Hypusine synthesis from eIF5A-lysine; . ChiTaRS EIF5A; human; . EvolutionaryTrace P63241; -; . GeneWiki EIF5A; -; . GenomeRNAi 1984; -; . PMAP-CutDB P63241; -; . PRO PR:P63241; -; . Proteomes UP000005640; Chromosome 17; . Bgee ENSG00000132507; -; . CleanEx HS_EIF5A; -; . ExpressionAtlas P63241; baseline and differential; . Genevisible P63241; HS; . GO GO:0005642; C:annulate lamellae; IDA:UniProtKB; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005643; C:nuclear pore; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0047485; F:protein N-terminus binding; IPI:UniProtKB; . GO GO:0043022; F:ribosome binding; IEA:InterPro; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0003746; F:translation elongation factor activity; ISS:UniProtKB; . GO GO:0017070; F:U6 snRNA binding; IDA:UniProtKB; . GO GO:0006915; P:apoptotic process; IDA:UniProtKB; . GO GO:0006406; P:mRNA export from nucleus; IMP:UniProtKB; . GO GO:0006913; P:nucleocytoplasmic transport; IMP:UniProtKB; . GO GO:0008612; P:peptidyl-lysine modification to peptidyl-hypusine; TAS:Reactome; . GO GO:0043065; P:positive regulation of apoptotic process; IEA:Ensembl; . GO GO:0008284; P:positive regulation of cell proliferation; IGI:UniProtKB; . GO GO:0045901; P:positive regulation of translational elongation; ISS:UniProtKB; . GO GO:0045905; P:positive regulation of translational termination; IEA:InterPro; . GO GO:0006611; P:protein export from nucleus; IMP:UniProtKB; . GO GO:0006452; P:translational frameshifting; IEA:InterPro; . Gene3D 2.30.30.30; -; 1; . InterPro IPR012340; NA-bd_OB-fold; . InterPro IPR014722; Rib_L2_dom2; . InterPro IPR019769; Trans_elong_IF5A_hypusine_site; . InterPro IPR001884; Transl_elong_IF5A; . InterPro IPR020189; Transl_elong_IF5A_C; . InterPro IPR008991; Translation_prot_SH3-like; . PANTHER PTHR11673; PTHR11673; 1; . Pfam PF01287; eIF-5a; 1; . PIRSF PIRSF003025; eIF5A; 1; . SMART SM01376; eIF-5a; 1; . SUPFAM SSF50104; SSF50104; 1; . SUPFAM SSF50249; SSF50249; 1; . TIGRFAMs TIGR00037; eIF_5A; 1; . PROSITE PS00302; IF5A_HYPUSINE; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

[Home]